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    5. The MAK Collection for Occupational Health and Safety
    6. Article
    7. Volume 4 (2019)
    8. Issue 4
    9. Addendum zu Pentachlorphenol. Beurteilungswerte in biologischem Material
Cover: The MAK Collection for Occupational Health and Safety

The MAK Collection for Occupational Health and Safety

German Research Foundation – Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area
(MAK Commission)

ISSN 2509-2383



Addendum zu Pentachlorphenol

Beurteilungswerte in biologischem Material

Dirk Walter1
  Hans Drexler2
  Andrea Hartwig3
  MAK Commission4

1 Justus-Liebig-Universität Gießen, Institut und Poliklinik für Arbeits- und Sozialmedizin, Aulweg 129, 35392 Gießen, Deutschland
2 Friedrich-Alexander-Universität Erlangen-Nürnberg, Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin, Henkestraße 9–11, 91054 Erlangen, Deutschland
3 Institut für Angewandte Biowissenschaften, Abteilung Lebensmittelchemie und Toxikologie, Karlsruher Institut für Technologie (KIT), Adenauerring 20a, Geb. 50.41, 76131 Karlsruhe, Deutschland
4 Ständige Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Deutschland

Abstract

In 2018, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the correlation (EKA) between inhalational exposure to pentachlorophenol and urinary pentachlorophenol excretion. The re‐evaluation of the available literature led to the conclusion that the present data are limited and all available studies show limitations regarding to air exposure assessment and characterisation of possible dermal exposure of the workers. Thus, the EKA correlation was withdrawn.

Keywords

pentachlorophenol, PCP, 2,3,4,5,6-pentachlorophenol, exposure equivalents for carcinogenic substances, EKA