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    9. Addendum zu 1,1,1‐Trichlorethan. Beurteilungswerte in biologischem Material
Cover: The MAK Collection for Occupational Health and Safety

The MAK Collection for Occupational Health and Safety

German Research Foundation – Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area
(MAK Commission)

ISSN 2509-2383



Addendum zu 1,1,1‐Trichlorethan

Beurteilungswerte in biologischem Material

Hermann Maximilian Bolt1
  Hans Drexler2
  Andrea Hartwig3
  MAK Commission4

1 Leibniz-Institut für Arbeitsforschung an der TU Dortmund, Ardeystraße 67, 44139 Dortmund, Deutschland
2 Friedrich-Alexander-Universität Erlangen-Nürnberg, Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin, Henkestraße 9–11, 91054 Erlangen, Deutschland
3 Institut für Angewandte Biowissenschaften, Abteilung Lebensmittelchemie und Toxikologie, Karlsruher Institut für Technologie (KIT), Adenauerring 20a, Geb. 50.41, 76131 Karlsruhe, Deutschland
4 Ständige Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Deutschland

Abstract

In 2018, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the Biological Tolerance Value (BAT) of 1,1,1‐trichloroethane (methyl chloroform) after the MAK value for 1,1,1‐trichloroethane has been lowered from 200 ml/m3 to 100 ml/m3. In consequence, the previous BAT value of 550 µg 1,1,1‐trichloroethane per l blood was adjusted to 275 µg 1,1,1‐trichloroethane per l blood. The sampling conditions (at the beginning of the next shift, after several shifts) remain unchanged.

Keywords

1,1,1-trichloroethane, methyl chloroform, chlorothene, biological tolerance value, BAT value, developmental toxicity