Magnesium oxide, insoluble (Sintermagnesite) (respirable fraction)
MAK Value Documentation, addendum – Translation of the German version from 2018
Andrea Hartwig1 (Chair of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Deutsche Forschungsgemeinschaft)MAK Commission2
1 Institute of Applied Biosciences, Department of Food Chemistry and Toxicology, Karlsruhe Institute of Technology (KIT), Adenauerring 20a, Building 50.41, 76131 Karlsruhe, Germany
2 Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Germany
Abstract
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has reevaluated magnesium oxide. Magnesium oxide, sintermagnesite [1309‐48‐4], is a biopersistent granular dust. Therefore, the respirable fraction of magnesium oxide dust has been classified in Carcinogen Category 4 and a MAK value of 0.3 mg/m3 × material density was established for the respirable fraction in analogy to the other biopersistent granular dusts. Additionally for this fraction the Peak Limitation Category II with an excursion factor of 8 was established. Since magnesium oxide is not systemically distributed and accumulates only locally in the lungs, no developmental effects due to this dust are expected to occur at the MAK value of 0.3 mg/m3 × material density (respirable, R‐fraction). Magnesium oxide has accordingly been classified in Pregnancy Risk Group C. Magnesium oxide is not designated with either “Sa” or “Sh” or “H”.
