Cover: The MAK Collection for Occupational Health and Safety

The MAK Collection for Occupational Health and Safety

Deutsche Forschungsgemeinschaft – Ständige Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe (MAK-Kommission)

ISSN 2509-2383



Addendum zu Methanol

Beurteilungswerte in biologischem Material

Patricia Kreis1
Britta Brinkmann1
  Hans Drexler2
  Andrea Hartwig1
  MAK Commission3

1 Institut für Angewandte Biowissenschaften, Abteilung Lebensmittelchemie und Toxikologie, Karlsruher Institut für Technologie (KIT), Adenauerring 20a, Geb. 50.41, 76131 Karlsruhe, Deutschland
2 Friedrich-Alexander-Universität Erlangen-Nürnberg, Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin, Henkestraße 9–11, 91054 Erlangen, Deutschland
3 Ständige Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Deutschland

Abstract

In 2018, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has lowered the maximum concentration at the workplace (MAK value) to 100 ml methanol/m3. The BAT value was correlated to the MAK value. Therefore, the BAT value has to be re‐evaluated.

After 8‐hour exposure of test persons to 100 ml methanol/m3 with physical activity, a concentration of 15 mg methanol/l urine was measured. This is in line with the results of a field study in which a methanol concentration of approximately 100 ml/m3 corresponded to around 20 mg methanol/l urine.

Therefore, the BAT value has now been set to 15 mg methanol/l urine. Sampling time is at the end of exposure or the end of the working shift, for long‐term exposure at the end of the shift after several shifts.


Keywords

Methanol, Methylalkohol, Carbinol, Biologischer Arbeitsstoff-Toleranzwert, BAT-Wert, Entwicklungstoxizität