Trimethylamine

MAK Value Documentation, addendum – Translation of the German version from 2018

  Andrea Hartwig¹ (Chair of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Deutsche Forschungsgemeinschaft)
  MAK Commission<sup>2

1</sup> Institute of Applied Biosciences, Department of Food Chemistry and Toxicology, Karlsruhe Institute of Technology (KIT), Adenauerring 20a, Building 50.41, 76131 Karlsruhe, Germany
² Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Germany

Abstract

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated a momentary value for trimethylamine [75‐50‐3].

Critical effect is the irritation of the respiratory epithelia in the nose of rats and a maximum concentration at the workplace (MAK value) of 2 ml/m³ has been set. This value was established by analogy with cyclohexylamine. In addition to the MAK value, a momentary value of 5 ml/m³ for cyclohexylamine has been established which must not be exceeded at any time to prevent from local irritation. Therefore, a momentary value of 5 ml/m³ is also set for N,N‐trimethylamine.

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