Trimethylamin
MAK-Begründung, Nachtrag
Andrea Hartwig1 (Vorsitz der Ständigen Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft)MAK Commission2
1 Institut für Angewandte Biowissenschaften, Abteilung Lebensmittelchemie und Toxikologie, Karlsruher Institut für Technologie (KIT), Adenauerring 20a, Geb. 50.41, 76131 Karlsruhe, Deutschland
2 Ständige Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe, Deutsche Forschungsgemeinschaft, Kennedyallee 40, 53175 Bonn, Deutschland
Abstract
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated a momentary value for trimethylamine [75‐50‐3].
Critical effect is the irritation of the respiratory epithelia in the nose of rats and a maximum concentration at the workplace (MAK value) of 2 ml/m3 has been set. This value was established by analogy with cyclohexylamine. In addition to the MAK value, a momentary value of 5 ml/m3 for cyclohexylamine has been established which must not be exceeded at any time to prevent from local irritation. Therefore, a momentary value of 5 ml/m3 is also set for N,N‐trimethylamine.



