TY  - CHAP
T1  - The cell biology of Dupuytren’s Disease
T2  - Living Textbook of Hand Surgery
AU  - Bayat, Ardeshir
AU  - Al-Himdani, Sarah
ED  - Böttcher, Richarda
N2  - Dupuytren’s Disease is a benign palmar fibromatosis characterised by progressive shortening of the palmar fascia, leading to significant deformity and impaired function of the hand. Having knowledge of the cellular biology is an essential part of understanding the disease, the treatment options and the high recurrence rate. Myofibroblasts are thought to play a key role in the pathogenesis of the disease though their origin is not clear. Progenitor stem cells originating from the skin overlying the nodule or perinodular fat have been identified as potential source of the myofibroblasts. Several key cytokines and growth factors that potentially play an important role in the development of the disease have been identified. 
PY  - 2016
DA  - 2016/04/27
DO  - 10.5680/lhhs000012
LA  - en
L1  - https://series.publisso.de/en/system/getFile/121
UR  - https://dx.doi.org/10.5680/lhhs000012
L2  - https://dx.doi.org/10.5680/lhhs000012
PB  - German Medical Science GMS Publishing House
CY  - Cologne
ER  -